Transforming precision medicine through in-depth genomics.

Novel genomic technologies for deep view into tumor biology, evolution, and treatment.

Led by a well-established team with advanced genome analysis, bioinformatics, and assay development expertise.

Founders

Ignaty Leshchiner, PhD

Ignaty Leshchiner, PhD

Co-Founder

Associate Professor in Computational Biomedicine at Boston University School of Medicine. Expert in cancer computational biology, genomic technologies, and AI methods for unraveling tumor development, treatment evasion, and metastasis progression.

Dimitri Livitz, PhD

Dimitri Livitz, PhD

Co-Founder, Head of Data Science

Head of Data Science and Genomics. Formerly at the Broad Institute of Harvard and MIT, co-author of high-profile publications in Nature, Nature Medicine, and Cell. PhD from Columbia University in Bayesian experimental design.

Paul Trukhanov

Paul Trukhanov

Co-Founder

Software Architect in Machine Learning at Dana-Farber Cancer Institute. Experienced startup entrepreneur with expertise in biotechnology, healthcare, and data-intensive software engineering, with two successful startup exits.

Elizaveta Leshchiner, PhD

Elizaveta Leshchiner, PhD

Co-Founder

Focused on experimental and computational cancer biology with strong expertise in technology and high-throughput assay development. PhD from Harvard University; leads a team of scientists at the Broad Institute of Harvard and MIT.

Andrew Jacobs, JD

Andrew Jacobs, JD

Co-Founder, CEO

As CEO Andy has a 40-year record of successfully starting, managing and growing multitude of small and medium sized companies, several of which were subsequently sold to public companies. He has served as CEO and a Board Member for companies in the area of computational services and data management for cancer patients, as well as in other fields, and has been heavily involved in several non-profit enterprises, including a foundation providing patient access to experimental cancer vaccines under FDA regulations.

Want to learn more about our team?

SmartRD Technology Platform

Ultra High Sensitivity Multi-Modal Liquid Biopsy

Ultra Deep Sequencing

Cell-free (cf) DNA sequencing and analysis with unparalleled depth and sensitivity

Unique Epigenetic Data

Comprehensive methylation and nucleosome profiling for deeper biological insights

AI/ML Platform

Proprietary computational platform for advanced analysis and biomarker discovery

An innovative, efficient, and transformative solution for monitoring disease progression and identifying clinically druggable targets.

cfDNA Sequencing

In-depth cfDNA analysis for treatment efficacy assessment, clonal evolution and resistance dynamics for biomarker discovery, revealing signal from all lesions.

Nature Medicine 2019

Subclonal Reconstruction

Evolution and resistance analysis of disease reveals latent trends and information invisible from bulk analysis, increasing statistical power in small cohorts.

Nature Medicine 2023

Identify Early Drivers

Establish previously unknown early genetic progression of cancers with unobtainable premalignant tissue for early detection, interception and prognostication.

Nature Cancer 2024